#81 – Debra Kimless, M.D. & Steve Goldner, J.D.: Cannabis – the latest science on CBD & THC
Summary

In this episode of the Peter Atia Drive podcast, the host discusses the topic of THC, CBD, and cannabis with two experts in the field, Dr. Deborah Kimless and Steve Goldner. The conversation covers the difference between THC and CBD, how they work in the body, and the safety issues surrounding vaping. The context emphasizes the importance of set and setting when using any substance and cautions against making assumptions about the potential for addiction in individuals.

The speaker discusses the potential use of THC and CBD for medical purposes, particularly for pain relief and sleep aid. They explain that THC can be effective for chronic pain, but there is a risk of tachyphylaxis or tolerance, which can lead to increased pain. They also discuss the potential benefits of using THC in combination with other drugs, such as opiates, to reduce the need for higher doses. The speaker also emphasizes the importance of understanding the dose and using small amounts of cannabinoids to avoid intoxication.

The discussion also revolves around the recent cases of acute toxicities related to vaping and the difficulty in identifying the clear cause. Chronic toxicity from vaping is uncertain since it hasn't been around long enough. Edibles require heating to extract the active ingredient, and the variability in preparation and digestion makes it difficult to expect a reliable and repeatable dosage experience.

The speaker discusses the benefits of cannabis products for pain relief and anxiety reduction, citing personal experiences of friends in law enforcement and healthcare. They also acknowledge the need for more research and caution against false claims and predatory companies. The speaker's company is pursuing FDA approval for several therapeutic indications, including PTSD, pain in humans and dogs, and osteoarthritis.

The context also discusses a company in Michigan that has obtained the first license to process cannabis grown within the state and turn it into various products such as tablets, gummy bears, and vape cartridges. The company has grown to have liaisons with subsidiary companies and affiliated companies, where they are growing about 5500 plants and have relationships with all of the 7080 dispensary stores throughout Michigan.

Overall, the episode aims to provide valuable information to those interested in the topic and may require further exploration as the field continues to evolve. The speakers emphasize the importance of credible research to avoid damaging the credibility of cannabis products and the need for patient safety when purchasing from legal dispensaries.