#42–Avrum Bluming, M.D. and Carol Tavris, Ph.D.: A compelling case for hormone replacement therapy
Summary

The Peter Atia Drive podcast recently featured an interview with Dr. Avram Blooming and Dr. Carol Tavis about their book, Estrogen Matters, which challenges the established medical entities and argues for the beneficial use of hormone replacement therapy (HRT) for women. The conversation covers the history of hormone replacement therapy, the Women's Health Initiative, and the clinical conditions for which hormone replacement therapy should be considered. The podcast emphasizes the importance of understanding the role of hormones in women's health and the need to challenge assumptions in medical practice.

The speakers discuss the decline of estrogen levels in women during menopause and how it can cause symptoms such as depression. The speakers also address the misconception that estrogen causes breast cancer and emphasize the importance of understanding the risks of heart disease for women. The conversation also touches on the personal experiences of the speakers and their motivations for discussing this topic.

The Women's Health Initiative study on hormone replacement therapy (HRT) and its alleged increased risk of breast cancer was not statistically significant. The study had several motives, including breaking into the noisy news cycle and getting attention. The study also raised questions about the role of synthetic progesterone and not having a uterus in breast cancer risk.

The podcast discusses the hypothesis that the difference in longevity between men and women is not due to women living longer, but rather due to women experiencing an abrupt loss of hormones while men experience a gradual loss. The discussion revolves around the benefits and downsides of Hormone Replacement Therapy (HRT) for women. The speakers suggest that HRT can decrease the risk of osteoporotic hip fractures by up to 50% and reduce the risk of colon cancer by 20-25%. However, there is a small increase in the incidence of pulmonary embolism and venous thromboembolism, and an increase in the incidence of gall bladder disease among women on hormones.

The book being discussed challenges established medical entities and argues for the beneficial use of hormone replacement therapy (HRT) for women. The Women's Health Initiative (WHI) study, which found negative effects of HRT, is criticized for its flawed methodology and misinterpretation of data. The book presents evidence supporting the benefits of HRT for women's health and longevity. The authors encourage readers to read the book and explore the sources and information provided to make their own informed conclusions.