#134 - James O’Keefe, M.D.: Preventing cardiovascular disease and the risk of too much exercise
Summary

In this episode of The Drive podcast, host Peter Etia interviews Dr. James O'Keefe, a cardiologist and medical director of the Charles and Barbara Dubock Cardio Health and Wellness Center. The conversation covers a wide range of topics related to heart health, including the history and evolution of treating blockages in arteries, the impact of exercise on the heart, the role of nutrition and specific nutrients, and pharmacologic agents used to treat heart disease. O'Keefe emphasizes the importance of prevention and proactive approaches to managing heart disease.

The podcast discusses the benefits of exercise and the importance of getting the right dose. The speakers emphasize the importance of finding the right balance of exercise to reap the benefits without overdoing it. The context also delves into the variables of cardiac output, heart rate, and stroke volume, and how they play together during exercise. The potential risks of extreme exercise on the heart and overall health, particularly for individuals over the age of 40, are also discussed. The podcast emphasizes the importance of distinguishing between training for peak performance versus training for longevity and overall health.

The podcast also discusses the relationship between diet and cardiovascular health, emphasizing the benefits of a diet that is high in healthy fats, low in refined carbohydrates, and includes plenty of nuts, extra virgin olive oil, fish, and vegetables. The speakers recommend a natural, whole-foods-based diet with salt added to taste. The podcast also discusses the potential benefits of SGLT2 inhibitors and the use of statins as a medication to improve cardiovascular health. The speakers emphasize the importance of individualized treatment plans based on a patient's specific needs and risk factors.

Finally, the podcast touches on the importance of supplements for heart and brain health, including omega-3 supplements and curcumin. The speakers note the importance of getting omega-3 from a clean source and mention their preference for Carlson's brand. Overall, the podcast provides a comprehensive overview of various topics related to heart health and emphasizes the importance of a proactive approach to managing cardiovascular disease.