#38–Francisco Gonzalez-Lima, Ph.D.: Alzheimer’s disease & the vascular hypothesis
Summary

In this podcast episode, host Peter Atia and guest Francisco Gonzalez Lima discuss Alzheimer's disease and the importance of understanding the disease's pathology. They discuss the vascular hypothesis of Alzheimer's disease, which suggests that the disease is primarily caused by impaired blood flow to the brain and impaired mitochondrial respiration. The conversation also highlights the complexity of the brain and the importance of functional brain mapping.

The discussion also covers the difficulty in accurately diagnosing dementia and the importance of considering functional changes in the brain. The conversation also touches on the relationship between cognitive impairment and aging, and the importance of maintaining cardiovascular health to prevent cognitive decline. The use of methylene blue as a potential treatment for Alzheimer's disease is also discussed, along with the controversy surrounding the use of ineffective drugs in Alzheimer's treatment.

The conversation emphasizes the importance of prevention rather than treatment of dementia, and suggests various approaches to improving mitochondrial function in the brain, including near-infrared light therapy, methylene blue, and a ketogenic diet. The podcast episode also briefly touches on the safety concerns surrounding some of these approaches.

In addition to discussing Alzheimer's disease, Peter Atia explains why he has chosen to rely on listener support instead of selling ads for his podcast. He believes that selling ads would compromise trust and prevent him from advocating for products he truly believes in. Instead, he offers exclusive content and discounts to subscribers who support his work.