Summary
In this podcast episode, the host welcomes a guest who works in professional cycling and has been working with a young cyclist named Tadej Pogacar. The guest explains the importance of physiological testing and metabolomics platforms in predicting performance in cycling. The conversation also touches on the use of cameras and data in sports, specifically in cycling and Formula 1 racing. The discussion then shifts to a specific stage in the Tour de France and the strategy employed by a particular cyclist. The context also discusses the exercise intensity at which mitochondria and oxidative capacity are stressed the most and the relationship between blood lactate levels and fat oxidation during exercise. The speaker discusses the role of epigenetics in training for athletes and the relationship between mitochondrial function, fat oxidation, and ketosis in non-elite athletes. The context discusses the use of lactate levels and other metrics to determine an individual's training zone for exercise. The speaker discusses the optimal frequency and duration of exercise for individuals and the importance of VO2 max and its correlation with longevity. The conversation also touches on the use of metformin as a medication for diabetes and the question of its long-term effects on mitochondrial function. Finally, the speakers discuss their research on cellular metabolism and mitochondrial function in sedentary individuals compared to active individuals.
