Summary
The podcast episode featuring Dr. Eric Verdin highlights the importance of leading a healthy lifestyle to regulate the aging process. The discussion covers the four main lifestyle interventions that can be used for this purpose: exercise, nutrition, calorie restriction mimetics, and rejuvenation. Specifically, the conversation delves into the benefits of a ketogenic diet and fasting for inducing ketosis, which has been shown to promote healthspan and increase lifespan. Dr. Verdin also discusses the potential use of beta-hydroxybutyrate (BHB) as a therapeutic agent and its role in energy metabolism, signaling, and regulation of longevity-related genes. The episode also explores the importance of biomarkers of aging to evaluate the effectiveness of interventions, and the role of NAD in aging, and how its levels decrease with age. Dr. Verdin and Rhonda conclude the interview by highlighting the need for further research in aging biology and the potential for the pharma and venture capital industries to contribute to this exciting field.
